Rational Design of Hit Compounds Targeting Staphylococcus aureus Threonyl-tRNA Synthetase
Rybak M, Gudzera O, Gorbatiuk O, Usenko O, Yarmoluk S, Tukalo M., ACS Omega, 2021;6;24910–18.
Role: Author
Oksana Gorbatiuk
Ph.D., Senior researcher
Description of the field of scientific research:
— Gene technologies, protein engineering, recombinant proteins;
— Therapeutic cytokines. Targeted drug delivery.
— Immunoaffinity chromatography and immunodiagnostic.
— Recombinant antibodies (scFv).
— Stem cells. Regenerative medicine.
— Mesenchymal stem cell-derived extracellular vesicles.
— Protein kinase and tRNA synthetase inhibitors.
List of duties:
She is a researcher at two Ukrainian Research institutes: the Institute of Molecular Biology and Genetics of the NAS of Ukraine (IMBG) and the State Institute of Genetic and Regenerative Medicine of NSC Institute of Cardiology, Clinical and Regenerative Medicine n.a. M.D. Strazhesko of NAMS of Ukraine.
Her research interests cover the study of the fundamental basis of injured organism renewal, the development and usage of gene and cell technologies for damaged cells and hereditary material replacement, biotechnological obtaining of therapeutic recombinant proteins, protein-protein interaction, targeted delivery of therapeutic drugs, and immunodiagnostic.
Professional experience:
2014 – present — Head of the Laboratory of Genetic Engineering and Biotechnology of State Institute of Genetic and Regenerative Medicine Head of the NSC "Institute of Cardiology, Clinical and Regenerative Medicine n.a. M.D.Strazhesko" of NAMS of Ukraine.
2013 – present — Cell Regulatory Mechanisms Department Research fellow, Institute of Molecular Biology and Genetics of NAS of Ukraine.
Member of the Ukrainian Biochemical Society from 2008.
Member of the Academic Council of the State Institute of Genetic and Regenerative. Medicine (National Scientific Center "Institute of Cardiology, Clinical and Regenerative Medicine n.a. M.D.Strazhesko" of NAMS of Ukraine) from 2014.
Head of Council of Young Scientists of the State Institute of Genetic and Regenerative. Medicine (National Scientific Center "Institute of Cardiology, Clinical and Regenerative. Medicine n.a. M.D.Strazhesko" of NAMS of Ukraine) (2019–2021).
Member of TERMIS (Tissue Engineering and Regenerative Medicine International Society) from 2022.