WNT/β-catenin pathway is a key regulator of cardiac function and energetic metabolism
Volodymyr V. Balatskyi, Adrian Sowka, Pawel Dobrzyn, Oksana O. Piven . Acta Physiologicaб 2023. 1,
Role: Author
Oksana Piven
Ph.D., professor
Description of the field of scientific research:
Oksana researches cardiogenesis, myocardium, canonical WNT cascade, autophagy, cardiomyocytes, metabolism, oxidative phosphorylation, cardiomyogenic reprogramming, CRISPR.
List of duties:
Oksana works in molecular genetics and regulation of adaptation of the mammalian heart to physical exertion and postnatal formation of the canonical WNT signaling pathway. Recent studies are focused on studying the function of the canonical WNT signaling cascade in maintaining the metabolic homeostasis of the heart.
Professional experience:
Since 2002, Oksana has worked at the Institute of Molecular Biology and Genetics of the National Academy of Sciences of Ukraine, Kyiv.
In 2005 and 2007, Oksana was an inviting scholar at the University of Pennsylvania School of Medicine. 2007 she was also awarded a FEBS Fellowship for Spetses International Summer School "Molecular Mechanisms of Regeneration" in Greece. In 2008, she was awarded an EMBO Fellowship for Practical Courses "Anatomy and Embryology of the Mouse" in Croatia. In 2011, she was awarded a FEBS Fellowship for the 26th European Cytoskeletal Forum (ECF) and EMBO-FEBS Lecture Course "Actin-Based Motility: From Molecules to Model Organisms," Italy. In 2012, she was awarded a short-term scholarship from the European Organization for Molecular Biology to the Max Planck Institute for Heart and Lung Research in Germany and an EMBO scholarship to attend a UK Correlative Light Electron Microscopy course.
In 2016, Oksana received a Post-Doctoral Short–Term Fellowship from the European Molecular Biology Organisation at the International Institute of Molecular and Cell Biology in Warsaw. In 2018 and 2021, the scientist completed the "Cre-lox technology in Mouse Modeling" and "Mouse Engineering" mini-courses.
Since 2019, she has been a member of the commission of the Presidium of the National Academy of Sciences of Ukraine for the protection of science, countering pseudoscience and falsification of scientific research.
In 2022, Oksana reviewed research projects submitted to the European Union Framework Program for Scientific Research and Innovation "Horizon 2020." In the same year, "Vikhola" published Oksana's book "GMO Free. The Truth and Horror Stories about Genetic Engineering." From 2022 to 2023, Oksana worked at the Nencki Institute of Experimental Biology, PAS.
Since 2023, she has been a member of the commission of the competition "Cambridge - NFSU 2022. Individual grants for conducting research (development) for Ukrainian scientists."
She is also today a reviewer in the journals "BMC Oral Health," "Journal of Orthopedic Surgery and Research," "Cytology and Genetics" and "Biopolymers and Cell."
Keywords:
Basic scientific publications:
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Cardiac-specific β-catenin deletion dysregulates energetic metabolism and mitochondrial function in perinatal cardiomyocytes
Volodymyr V. Balatskyi, Vasyl O. Vaskivskyi, Anna Myronova, Diana Avramets, Karim Abu Nahia, Larysa L. Macewicz, Tetiana P. Ruban, Dar'ya Yu. Kucherenko, Oleksandr O. Soldatkin, Iryna V. Lushnikova, Galyna G. Skibo, Cecilia L. Winata, Pawel Dobrzyn, Oksana O. Piven Mitochondrionю 2021. 60, 59-69.
Role: Author